SIRT7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SIRT7 full-length
Host
Human
Theoretical MW (kDa)
44.11
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SIRT7 antibody (H00051547-B01) by Western Blots.
SDS-PAGE Gel
SIRT7 transfected lysate.
Western Blot
Lane 1: SIRT7 transfected lysate ( 44.11 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SIRT7
Entrez GeneID
51547GeneBank Accession#
NM_016538.1Protein Accession#
NP_057622.1Gene Name
SIRT7
Gene Alias
MGC126840, MGC126842, SIR2L7
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
Omim ID
606212Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
silent mating type information regulation 2, S.cerevisiae, homolog 7|sir2-related protein type 7|sirtuin 7|sirtuin type 7
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