SIRT7 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SIRT7 protein.
Immunogen
SIRT7 (NP_057622.1, 1 a.a. ~ 400 a.a) full-length human protein.
Sequence
MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Cell lysate)
SIRT7 MaxPab polyclonal antibody. Western Blot analysis of SIRT7 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of SIRT7 expression in transfected 293T cell line (H00051547-T01) by SIRT7 MaxPab polyclonal antibody.
Lane 1: SIRT7 transfected lysate(44 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SIRT7 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SIRT7
Entrez GeneID
51547GeneBank Accession#
NM_016538.1Protein Accession#
NP_057622.1Gene Name
SIRT7
Gene Alias
MGC126840, MGC126842, SIR2L7
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
Omim ID
606212Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
silent mating type information regulation 2, S.cerevisiae, homolog 7|sir2-related protein type 7|sirtuin 7|sirtuin type 7
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