NCKIPSD rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NCKIPSD peptide using ARM Technology.
Immunogen
A synthetic peptide of human NCKIPSD is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NCKIPSD peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NCKIPSD
Entrez GeneID
51517GeneBank Accession#
NCKIPSDGene Name
NCKIPSD
Gene Alias
AF3P21, DIP, DIP1, MGC23891, ORF1, SPIN90, WASLBP, WISH
Gene Description
NCK interacting protein with SH3 domain
Omim ID
606671Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq
Other Designations
SH3 protein interacting with Nck, 90 kDa|dia interacting protein|diaphanous protein interacting protein
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Interactome
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