CHMP5 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CHMP5 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MNRLFGKAKPKAPPPSLTGCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CHMP5
Entrez GeneID
51510GeneBank Accession#
NM_016410.2Protein Accession#
NP_057494.2Gene Name
CHMP5
Gene Alias
C9orf83, CGI-34, HSPC177, PNAS-2, SNF7DC2
Gene Description
chromatin modifying protein 5
Omim ID
610900Gene Ontology
HyperlinkGene Summary
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM
Other Designations
OTTHUMP00000021197|SNF7 domain containing 2
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Interactome
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Pathway
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