REV1L (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human REV1L partial ORF ( NP_057400, 1097 a.a. - 1194 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SPAKTLPGACGSPQKLIDGFLKHEGPPAEKPLEELSASTSGVPGLSSLQSDPAGCVRPPAPNLAGAVEFNDVKTLLREWITTISDPMEEDILQVVKYC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (77); Rat (62)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — REV1
Entrez GeneID
51455GeneBank Accession#
NM_016316Protein Accession#
NP_057400Gene Name
REV1
Gene Alias
FLJ21523, MGC163283, MGC26225, REV1L
Gene Description
REV1 homolog (S. cerevisiae)
Omim ID
606134Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq
Other Designations
OTTHUMP00000161216|REV1- like|REV1-like
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Interactome
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Disease
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