PRRX2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PRRX2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PRRX2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PRRX2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PRRX2
Entrez GeneID
51450GeneBank Accession#
PRRX2Gene Name
PRRX2
Gene Alias
MGC19843, PMX2, PRX2
Gene Description
paired related homeobox 2
Omim ID
604675Gene Ontology
HyperlinkGene Summary
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq
Other Designations
OTTHUMP00000022344|paired mesoderm homeobox protein 2|paired-like homeodomain protein PRX2|predicted NUP98/PRRX2 fusion protein
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Disease
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