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ANAPC5 (Human) IP-WB Antibody Pair

  • Catalog # : H00051433-PW2
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00051433-PW2
    Immunoprecipitation of ANAPC5 transfected lysate using rabbit polyclonal anti-ANAPC5 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ANAPC5.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-ANAPC5 (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-ANAPC5 (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Gene Name:
  • ANAPC5
  • Gene Alias:
  • APC5
  • Gene Description:
  • anaphase promoting complex subunit 5
  • Gene Summary:
  • This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq
  • Other Designations:
  • anaphase-promoting complex subunit 5,cyclosome subunit 5
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