Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

PRKAG2

Gene Alias

AAKG, AAKG2, CMH6, H91620p, WPWS

Gene Description

protein kinase, AMP-activated, gamma 2 non-catalytic subunit

Omim ID

Gene Ontology

Gene Summary

AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Other Designations

AMP-activated protein kinase gamma2 subunit|AMPK gamma2