ATP6V1D polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ATP6V1D.
Immunogen
ATP6V1D (NP_057078, 69 a.a. ~ 168 a.a) partial recombinant protein with GST tag.
Sequence
LAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYELTGLARGGEQLAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ATP6V1D
Entrez GeneID
51382GeneBank Accession#
NM_015994Protein Accession#
NP_057078Gene Name
ATP6V1D
Gene Alias
ATP6M, VATD, VMA8
Gene Description
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
Omim ID
609398Gene Ontology
HyperlinkGene Summary
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq
Other Designations
ATPase, H+ transporting lysosomal, member M|ATPase, H+ transporting, lysosomal (vacuolar proton pump)|ATPase, H+ transporting, lysosomal 34kD, V1 subunit D|ATPase, H+ transporting, lysosomal, 28 kD accessory protein|H(+)-transporting two-sector ATPase|H(+
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Interactome
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Disease
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