EDD1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human EDD1 partial ORF ( NP_056986, 2677 a.a. - 2774 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UBR5
Entrez GeneID
51366GeneBank Accession#
NM_015902Protein Accession#
NP_056986Gene Name
UBR5
Gene Alias
DD5, EDD, EDD1, FLJ11310, HYD, KIAA0896, MGC57263
Gene Description
ubiquitin protein ligase E3 component n-recognin 5
Omim ID
608413Gene Ontology
HyperlinkGene Summary
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq
Other Designations
E3 identified by differential display|E3 ubiquitin protein ligase, HECT domain containing, 1|hyperplastic discs protein homolog|progestin induced protein|ubiquitin-protein ligase
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Interactome
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Pathway
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