CDC40 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CDC40 partial ORF ( NP_056975.1, 393 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Interspecies Antigen Sequence
Mouse (98); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CDC40
Entrez GeneID
51362GeneBank Accession#
NM_015891Protein Accession#
NP_056975.1Gene Name
CDC40
Gene Alias
EHB3, FLJ10564, MGC102802, PRP17, PRPF17
Gene Description
cell division cycle 40 homolog (S. cerevisiae)
Omim ID
605585Gene Ontology
HyperlinkGene Summary
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq
Other Designations
EH-binding protein 3|OTTHUMP00000016997|cell division cycle 40 homolog|pre-mRNA splicing factor 17
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Interactome
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Disease
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