HOOK1 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of HOOK1 transfected lysate using rabbit polyclonal anti-HOOK1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-HOOK1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-HOOK1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-HOOK1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — HOOK1
Entrez GeneID
51361Gene Name
HOOK1
Gene Alias
HK1, MGC10642
Gene Description
hook homolog 1 (Drosophila)
Omim ID
607820Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000010548|hook homolog 1
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Interactome
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Disease
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