FZR1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human FZR1 full-length ORF ( AAH13413.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQYQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLVTRIR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
80.08
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FZR1
Entrez GeneID
51343GeneBank Accession#
BC013413Protein Accession#
AAH13413.1Gene Name
FZR1
Gene Alias
CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242
Gene Description
fizzy/cell division cycle 20 related 1 (Drosophila)
Omim ID
603619Gene Ontology
HyperlinkOther Designations
CDC20-like 1b|Fzr1 protein|fizzy-related protein
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Interactome
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Pathway
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Publication Reference
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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li.
Cell Death and Differentiation 2023 Feb; 30(2):527.
Application:Pull-Down, Recombinant proteins.
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Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.
Tsunematsu T, Takihara Y, Ishimaru N, Pagano M, Takata T, Kudo Y.
Nature Communications 2013 May; 4:1885.
Application:Func, Human, HeLa cells.
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Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
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