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Last updated: 2017/10/22

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SPG21 Pre-design Chimera RNAi

  • Catalog # : H00051324-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens spastic paraplegia 21 (autosomal recessive, Mast syndrome) (SPG21), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_016630
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • SPG21
  • Gene Alias:
  • ACP33,BM-019,GL010,MASPARDIN,MAST
  • Gene Description:
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome)
  • Gene Summary:
  • The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • acid cluster protein 33,spastic paraplegia 21
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