FKBP11 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human FKBP11 full-length ORF ( NP_057678.1, 1 a.a. - 201 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTLRPSLLPLHLLLLLLLSAAVCRAEAGLETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIALIRANYWLKLVKGILPLVGMAMVPALLGLIGYHLYRKANRPKVSKKKLKEEKRNKSKKK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
48.6
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FKBP11
Entrez GeneID
51303GeneBank Accession#
NM_016594.1Protein Accession#
NP_057678.1Gene Name
FKBP11
Gene Alias
FKBP19, MGC54182
Gene Description
FK506 binding protein 11, 19 kDa
Omim ID
610571Gene Ontology
HyperlinkGene Summary
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM
Other Designations
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