PLUNC (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PLUNC full-length ORF ( AAH12549.1, 1 a.a. - 256 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MFQTGGLIVFYGLLAQTMAQFGGLPVPLDQTLPLNVNPALPLSPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILKPGGGTSGGLLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIKV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
53.90
Interspecies Antigen Sequence
Mouse (66); Rat (67)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PLUNC
Entrez GeneID
51297GeneBank Accession#
BC012549Protein Accession#
AAH12549.1Gene Name
PLUNC
Gene Alias
LPLUNC3, LUNX, NASG, SPLUNC1, SPURT, bA49G10.5
Gene Description
palate, lung and nasal epithelium associated
Omim ID
607412Gene Ontology
HyperlinkGene Summary
This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known. [provided by RefSeq
Other Designations
OTTHUMP00000030625|OTTHUMP00000030626|OTTHUMP00000030627|ligand-binding protein RYA3|nasopharyngeal carcinoma-related protein|secretory protein in upper respiratory tracts|tracheal epithelium enriched protein
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Interactome
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Disease
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Publication Reference
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Identification of Lipocalin and Apolipoprotein A1 as Biomarkers of Chronic Obstructive Pulmonary Disease.
Nicholas BL, Skipp P, Barton S, Singh D, Bagmane D, Mould R, Angco G, Ward J, Guha-Niyogi B, Wilson S, Howarth P, Davies DE, Rennard S, O'Connor CD, Djukanovic R.
American Journal of Respiratory and Critical Care Medicine 2010 May; 181(10):1049.
Application：ELISA, WB-Re, Human, Sputum samples.
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Identification of Lipocalin and Apolipoprotein A1 as Biomarkers of Chronic Obstructive Pulmonary Disease.
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