TLR7 monoclonal antibody (M07), clone 4G6
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More Files
- More Functions
Western Blot (Cell lysate)
TLR7 monoclonal antibody (M07), clone 4G6. Western Blot analysis of TLR7 expression in Daoy.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TLR7 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TLR7.
Immunogen
TLR7 (NP_057646, 27 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ARWFPKTLPCDVTLDVPKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFSGL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TLR7 monoclonal antibody (M07), clone 4G6. Western Blot analysis of TLR7 expression in Daoy.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TLR7 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — TLR7
Entrez GeneID
51284GeneBank Accession#
NM_016562Protein Accession#
NP_057646Gene Name
TLR7
Gene Alias
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Gene Description
toll-like receptor 7
Omim ID
300365Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq
Other Designations
OTTHUMP00000022919
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Interactome
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Pathway
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Disease
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