CLEC1B monoclonal antibody (M02), clone 1C10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLEC1B.
Immunogen
CLEC1B (NP_057593, 128 a.a. ~ 229 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISENMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.96 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of CLEC1B transfected lysate using anti-CLEC1B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CLEC1B MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CLEC1B is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CLEC1B
Entrez GeneID
51266GeneBank Accession#
NM_016509Protein Accession#
NP_057593Gene Name
CLEC1B
Gene Alias
1810061I13Rik, CLEC2, CLEC2B, PRO1384, QDED721
Gene Description
C-type lectin domain family 1, member B
Omim ID
606783Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM
Other Designations
C-type lectin-like receptor-2
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Interactome
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Disease
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Publication Reference
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C-type lectin like-receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets.
Manne BK, Badolia R, Dangelmaier CA, Kunapuli SP.
Biochemical Pharmacology 2015 Jan; 93(2):163.
Application:IP-WB, Human, Platelets.
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C-type lectin like-receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets.
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