CDKL3 monoclonal antibody (M03), clone 4F1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDKL3.
Immunogen
CDKL3 (AAH41799.1, 322 a.a. ~ 420 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRVIKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CDKL3 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — CDKL3
Entrez GeneID
51265GeneBank Accession#
BC041799Protein Accession#
AAH41799.1Gene Name
CDKL3
Gene Alias
NKIAMRE
Gene Description
cyclin-dependent kinase-like 3
Omim ID
608459Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
serine-threonine protein kinase NKIAMRE
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Interactome
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Disease
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