DSCR5 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human DSCR5 partial ORF ( NP_710149, 77 a.a. - 134 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.12
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PIGP
Entrez GeneID
51227GeneBank Accession#
NM_153682Protein Accession#
NP_710149Gene Name
PIGP
Gene Alias
DCRC, DCRC-S, DSCR5, DSRC
Gene Description
phosphatidylinositol glycan anchor biosynthesis, class P
Omim ID
605938Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
Down syndrome critical region gene 5|Down syndrome critical region protein 5|Down syndrome critical region protein C|OTTHUMP00000109076|OTTHUMP00000109079|phosphatidylinositol N-acetylglucosaminyltransferase subunit P|phosphatidylinositol glycan, class P|
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Interactome
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Pathway
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Disease
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