PIGP monoclonal antibody (M01), clone 2E7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PIGP.
Immunogen
PIGP (NP_710149, 77 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.12 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PIGP is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — PIGP
Entrez GeneID
51227GeneBank Accession#
NM_153682Protein Accession#
NP_710149Gene Name
PIGP
Gene Alias
DCRC, DCRC-S, DSCR5, DSRC
Gene Description
phosphatidylinositol glycan anchor biosynthesis, class P
Omim ID
605938Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
Down syndrome critical region gene 5|Down syndrome critical region protein 5|Down syndrome critical region protein C|OTTHUMP00000109076|OTTHUMP00000109079|phosphatidylinositol N-acetylglucosaminyltransferase subunit P|phosphatidylinositol glycan, class P|
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Interactome
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Pathway
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Disease
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