DUSP13 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DUSP13 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DUSP13 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DUSP13 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DUSP13
Entrez GeneID
51207GeneBank Accession#
DUSP13Gene Name
DUSP13
Gene Alias
BEDP, DUSP13A, DUSP13B, FLJ32450, MDSP, SKRP4, TMDP
Gene Description
dual specificity phosphatase 13
Gene Ontology
HyperlinkGene Summary
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq
Other Designations
OTTHUMP00000019875|OTTHUMP00000060197|branching-enzyme interacting dual-specificity protein phosphatase|dual-specificity phosphatase SKRP4|muscle-restricted dual specificity phosphatase
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Interactome
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Disease
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