HSD17B14 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human HSD17B14 full-length ORF ( NP_057330.2, 1 a.a. - 270 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.7
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HSD17B14
Entrez GeneID
51171GeneBank Accession#
NM_016246.2Protein Accession#
NP_057330.2Gene Name
HSD17B14
Gene Alias
DHRS10, SDR47C1, retSDR3
Gene Description
hydroxysteroid (17-beta) dehydrogenase 14
Gene Ontology
HyperlinkGene Summary
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM
Other Designations
dehydrogenase/reductase (SDR family) member 10|retinal short-chain dehydrogenase/reductase 3|short chain dehydrogenase/reductase family 47C, member 1
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