HSD17B14 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HSD17B14 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HSD17B14 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HSD17B14 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HSD17B14
Entrez GeneID
51171GeneBank Accession#
HSD17B14Gene Name
HSD17B14
Gene Alias
DHRS10, SDR47C1, retSDR3
Gene Description
hydroxysteroid (17-beta) dehydrogenase 14
Gene Ontology
HyperlinkGene Summary
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM
Other Designations
dehydrogenase/reductase (SDR family) member 10|retinal short-chain dehydrogenase/reductase 3|short chain dehydrogenase/reductase family 47C, member 1
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Interactome
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