SLC45A2 monoclonal antibody (M01), clone 2F4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant SLC45A2.
Immunogen
SLC45A2 (AAH03597, 1 a.a. ~ 243 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGSNSGQAGRHIYKSLADDGPFDSVEPPKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTDSQGNDIKVTAESTGEHASSLPLPLHQPPHWMDGLPVQHAVLHRFHGPDCVPRGSL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (52.47 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MATP monoclonal antibody (M01), clone 2F4 Western Blot analysis of MATP expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC45A2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — SLC45A2
Entrez GeneID
51151GeneBank Accession#
BC003597Protein Accession#
AAH03597Gene Name
SLC45A2
Gene Alias
1A1, AIM1, MATP, SHEP5
Gene Description
solute carrier family 45, member 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
melanoma antigen AIM1|membrane associated transporter|membrane-associated transporter protein|underwhite
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Interactome
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Disease
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Publication Reference
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Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity.
Bin BH, Bhin J, Yang SH, Shin M, Nam YJ, Choi DH, Shin DW, Lee AY, Hwang D, Cho EG, Lee TR.
PLoS One 2015 Jun; 10(6):e0129273.
Application:IF, WB-Ce, WB-Tr, Human, HeLa, MNT-1, SK-MEL1, SK-MEL2, SK-MEL3, SK-MEL5, WM2664 cells.
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Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity.
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