ING4 monoclonal antibody (M01), clone 8F7
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More Files
- More Functions
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ING4.
Immunogen
ING4 (AAH07781.1, 1 a.a. ~ 249 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (97)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.9 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ING4 expression in transfected 293T cell line by ING4 monoclonal antibody (M01), clone 8F7.
Lane 1: ING4 transfected lysate (Predicted MW: 28.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ING4 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — ING4
Entrez GeneID
51147GeneBank Accession#
BC007781.2Protein Accession#
AAH07781.1Gene Name
ING4
Gene Alias
MGC12557, my036, p29ING4
Gene Description
inhibitor of growth family, member 4
Omim ID
608524Gene Ontology
HyperlinkGene Summary
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq
Other Designations
brain my036 protein|candidate tumor suppressor p33 ING1 homolog
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