HSD17B12 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant HSD17B12.
Immunogen
HSD17B12 (NP_057226, 203 a.a. ~ 271 a.a) partial recombinant protein with GST tag.
Sequence
SATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (78)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.7 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
HSD17B12 polyclonal antibody (A01), Lot # 051122JCO1 Western Blot analysis of HSD17B12 expression in A-431 ( Cat # L015V1 ).Western Blot (Cell lysate)
HSD17B12 polyclonal antibody (A01), Lot # 060803QCS1. Western Blot analysis of HSD17B12 expression in SJCRH30.Western Blot (Recombinant protein)
ELISA
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Gene Info — HSD17B12
Entrez GeneID
51144GeneBank Accession#
NM_016142Protein Accession#
NP_057226Gene Name
HSD17B12
Gene Alias
KAR, SDR12C1
Gene Description
hydroxysteroid (17-beta) dehydrogenase 12
Omim ID
609574Gene Ontology
HyperlinkGene Summary
The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.[supplied by OMIM
Other Designations
17beta-HSD type 12|3-ketoacyl-CoA reductase|short chain dehydrogenase/reductase family 12C, member 1|steroid dehydrogenase homolog
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Interactome
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Pathway
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Disease
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Publication Reference
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Overexpression of 17β-hydroxysteroid dehydrogenase type 1 increases the exposure of endometrial cancer to 17β-estradiol.
Cornel KM, Kruitwagen RF, Delvoux B, Visconti L, Van de Vijver KK, Day JM, Van Gorp T, Hermans RJ, Dunselman GA, Romano A.
The Journal of Clinical Endocrinology and Metabolism 2012 Apr; 97(4):E591.
Application:WB-Tr, Human, ECC1 cells.
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Overexpression of 17β-hydroxysteroid dehydrogenase type 1 increases the exposure of endometrial cancer to 17β-estradiol.
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