INSIG2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human INSIG2 full-length ORF ( AAH22475, 1 a.a. - 225 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAEGETEPPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQPLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAVYECKVIAEKSHQE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.49
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — INSIG2
Entrez GeneID
51141GeneBank Accession#
BC022475Protein Accession#
AAH22475Gene Name
INSIG2
Gene Alias
MGC26273
Gene Description
insulin induced gene 2
Omim ID
608660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. [provided by RefSeq
Other Designations
INSIG2 membrane protein|insulin induced protein 2
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Interactome
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Disease
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