MLXIPL monoclonal antibody (M01), clone 5B2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MLXIPL.
Immunogen
MLXIPL (NP_116569.1, 603 a.a. ~ 700 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MLXIPL is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — MLXIPL
Entrez GeneID
51085GeneBank Accession#
NM_032951Protein Accession#
NP_116569.1Gene Name
MLXIPL
Gene Alias
CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH, bHLHd14
Gene Description
MLX interacting protein-like
Omim ID
605678Gene Ontology
HyperlinkGene Summary
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq
Other Designations
Mlx interactor|OTTHUMP00000160457|OTTHUMP00000160458|WS basic-helix-loop-helix leucine zipper protein|Williams Beuren syndrome chromosome region 14|carbohydrate response element binding protein|carbohydrate-responsive element-binding protein
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Interactome
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Disease
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