EXOSC1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-EXOSC1 full-length
Host
Human
Theoretical MW (kDa)
21.56
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-EXOSC1 antibody (H00051013-B01) by Western Blots.
SDS-PAGE Gel
EXOSC1 transfected lysate
Western Blot
Lane 1: EXOSC1 transfected lysate ( 21.56 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — EXOSC1
Entrez GeneID
51013GeneBank Accession#
BC022067Protein Accession#
AAH22067Gene Name
EXOSC1
Gene Alias
CGI-108, CSL4, Csl4p, SKI4, Ski4p, hCsl4p, p13
Gene Description
exosome component 1
Omim ID
606493Gene Ontology
HyperlinkGene Summary
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq
Other Designations
3'-5' exoribonuclease CSL4 homolog|CSL4 exosomal core protein homolog|OTTHUMP00000020203|exosomal core protein CSL4|homolog of yeast exosomal core protein CSL4
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Interactome
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Pathway
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