EXOSC1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human EXOSC1 full-length ORF ( AAH22067, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
47.19
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EXOSC1
Entrez GeneID
51013GeneBank Accession#
BC022067Protein Accession#
AAH22067Gene Name
EXOSC1
Gene Alias
CGI-108, CSL4, Csl4p, SKI4, Ski4p, hCsl4p, p13
Gene Description
exosome component 1
Omim ID
606493Gene Ontology
HyperlinkGene Summary
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq
Other Designations
3'-5' exoribonuclease CSL4 homolog|CSL4 exosomal core protein homolog|OTTHUMP00000020203|exosomal core protein CSL4|homolog of yeast exosomal core protein CSL4
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Interactome
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Pathway
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