EXOSC1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EXOSC1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EXOSC1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EXOSC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EXOSC1
Entrez GeneID
51013GeneBank Accession#
EXOSC1Gene Name
EXOSC1
Gene Alias
CGI-108, CSL4, Csl4p, SKI4, Ski4p, hCsl4p, p13
Gene Description
exosome component 1
Omim ID
606493Gene Ontology
HyperlinkGene Summary
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq
Other Designations
3'-5' exoribonuclease CSL4 homolog|CSL4 exosomal core protein homolog|OTTHUMP00000020203|exosomal core protein CSL4|homolog of yeast exosomal core protein CSL4
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