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EXOSC1 rabbit monoclonal antibody

  • Catalog # : H00051013-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human EXOSC1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human EXOSC1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human EXOSC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Gene Name:
  • EXOSC1
  • Gene Alias:
  • CGI-108,CSL4,Csl4p,SKI4,Ski4p,hCsl4p,p13
  • Gene Description:
  • exosome component 1
  • Gene Summary:
  • This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq
  • Other Designations:
  • 3'-5' exoribonuclease CSL4 homolog,CSL4 exosomal core protein homolog,OTTHUMP00000020203,exosomal core protein CSL4,homolog of yeast exosomal core protein CSL4
  • Gene Pathway
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