PARD6A 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PARD6A full-length
Host
Human
Theoretical MW (kDa)
37.3
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PARD6A antibody (H00050855-B01) by Western Blots.
SDS-PAGE Gel
PARD6A transfected lysate
Western Blot
Lane 1: PARD6A transfected lysate ( 37.3 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PARD6A
Entrez GeneID
50855GeneBank Accession#
NM_001037281Protein Accession#
NP_001032358Gene Name
PARD6A
Gene Alias
PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Gene Description
par-6 partitioning defective 6 homolog alpha (C. elegans)
Omim ID
607484Gene Ontology
HyperlinkGene Summary
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
Tax-interacting protein 40|par-6 partitioning defective 6 homolog alpha|partitioning defective-6 homolog alpha|partitioning-defective protein 6
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Interactome
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Disease
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