F11R (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (71)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of F11R transfected lysate using rabbit polyclonal anti-F11R and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-F11R.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-F11R (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-F11R (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — F11R
Entrez GeneID
50848Gene Name
F11R
Gene Alias
CD321, JAM, JAM-1, JAM-A, JAM1, JAMA, JCAM, KAT, PAM-1
Gene Description
F11 receptor
Omim ID
605721Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq
Other Designations
OTTHUMP00000027880|OTTHUMP00000027881|junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule
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