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PNPLA8 rabbit monoclonal antibody

  • Catalog # : H00050640-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PNPLA8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PNPLA8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PNPLA8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • PNPLA8
  • Gene Alias:
  • IPLA2(GAMMA),IPLA2-2,IPLA2G
  • Gene Description:
  • patatin-like phospholipase domain containing 8
  • Gene Summary:
  • Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM
  • Other Designations:
  • iPLA2 gamma,intracellular membrane-associated calcium-independent phospholipase A2 gamma,membrane-associated calcium-independent phospholipase A2 gamma
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