GEMIN4 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GEMIN4 partial ORF ( NP_056536, 959 a.a. - 1057 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GEMIN4
Entrez GeneID
50628GeneBank Accession#
NM_015721Protein Accession#
NP_056536Gene Name
GEMIN4
Gene Alias
DKFZp434B131, DKFZp434D174, HC56, HCAP1, HHRF-1, p97
Gene Description
gem (nuclear organelle) associated protein 4
Omim ID
606969Gene Ontology
HyperlinkGene Summary
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
HCC-associated protein 1|component of gems 4|gemin 4
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Interactome
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Disease
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