GEMIN4 monoclonal antibody (M04A), clone 4E3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GEMIN4.
Immunogen
GEMIN4 (NP_056536, 959 a.a. ~ 1057 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GEMIN4
Entrez GeneID
50628GeneBank Accession#
NM_015721Protein Accession#
NP_056536Gene Name
GEMIN4
Gene Alias
DKFZp434B131, DKFZp434D174, HC56, HCAP1, HHRF-1, p97
Gene Description
gem (nuclear organelle) associated protein 4
Omim ID
606969Gene Ontology
HyperlinkGene Summary
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
HCC-associated protein 1|component of gems 4|gemin 4
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Interactome
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Disease
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