DEF6 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human DEF6 full-length ORF ( AAH17504, 1 a.a. - 336 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGLSVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTATRTYEMSASDTRQRQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
62.7
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DEF6
Entrez GeneID
50619GeneBank Accession#
BC017504Protein Accession#
AAH17504Gene Name
DEF6
Gene Alias
IBP, SLAT
Gene Description
differentially expressed in FDCP 6 homolog (mouse)
Omim ID
610094Gene Ontology
HyperlinkGene Summary
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM
Other Designations
IRF4-binding protein|OTTHUMP00000016251|differentially expressed in FDCP 6 homolog
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Interactome
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Disease
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