ITSN2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ITSN2 partial ORF ( NP_006268, 471 a.a. - 571 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ITSN2
Entrez GeneID
50618GeneBank Accession#
NM_006277Protein Accession#
NP_006268Gene Name
ITSN2
Gene Alias
KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP
Gene Description
intersectin 2
Omim ID
604464Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined. [provided by RefSeq
Other Designations
SH3 domain protein 1B|SH3P18-like WASP associated protein
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Interactome
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Disease
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