MINK1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MINK1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MINK1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MINK1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MINK1
Entrez GeneID
50488GeneBank Accession#
MINK1Gene Name
MINK1
Gene Alias
B55, MAP4K6, MGC21111, MINK, YSK2, ZC3, hMINK, hMINKbeta
Gene Description
misshapen-like kinase 1 (zebrafish)
Omim ID
609426Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq
Other Designations
GCK family kinase MINK|misshapen/NIK-related kinase|serine/threonine protein kinase
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Interactome
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Disease
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