PLA2G3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLA2G3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLA2G3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLA2G3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLA2G3
Entrez GeneID
50487GeneBank Accession#
PLA2G3Gene Name
PLA2G3
Gene Alias
GIII-SPLA2, SPLA2III
Gene Description
phospholipase A2, group III
Omim ID
611651Gene Ontology
HyperlinkGene Summary
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]).[supplied by OMIM
Other Designations
group III secreted phospholipase A2|phosphatidylcholine 2-acylhydrolase GIII
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Pathway
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Disease
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