SMARCAL1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SMARCAL1 partial ORF ( NP_054859, 491 a.a. - 599 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FTWEQAFLRWLPSLSPDCINVVVTGKDRLTAGLINIVSFDLLSKLEKQLKTPFKVVIIDESHFLKNSRTARCRAAMPVLKVAKRVILLSGTPAMSRPAELYTQIIAVKP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Mouse (71); Rat (73)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SMARCAL1
Entrez GeneID
50485GeneBank Accession#
NM_014140Protein Accession#
NP_054859Gene Name
SMARCAL1
Gene Alias
HARP, HHARP
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq
Other Designations
HepA-related protein|OTTHUMP00000164057|SMARCA-like protein 1|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1
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Interactome
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Disease
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