KCNIP1 monoclonal antibody (M10), clone 3D9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant KCNIP1.
Immunogen
KCNIP1 (AAH50375, 1 a.a. ~ 216 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGAVMGTFSSLQTKQRRPSKDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEDTFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (49.5 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KCNIP1 expression in transfected 293T cell line by KCNIP1 monoclonal antibody (M10), clone 3D9.
Lane 1: KCNIP1 transfected lysate (Predicted MW: 25.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNIP1 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — KCNIP1
Entrez GeneID
30820GeneBank Accession#
BC050375Protein Accession#
AAH50375Gene Name
KCNIP1
Gene Alias
KCHIP1, MGC95, VABP
Gene Description
Kv channel interacting protein 1
Omim ID
604660Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms. [provided by RefSeq
Other Designations
A-type potassium channel modulatory protein 1|potassium channel interacting protein 1|vesicle APC-binding protein
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Interactome
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Disease
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