CSEN monoclonal antibody (M01A), clone 2B3-A1
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of KCNIP3 expression in transfected 293T cell line by CSEN monoclonal antibody (M01A), clone 2B3-A1.
Lane 1: KCNIP3 transfected lysate (Predicted MW: 29.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (53.9 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CSEN.
Immunogen
CSEN (AAH12850, 1 a.a. ~ 256 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (92)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (53.9 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KCNIP3 expression in transfected 293T cell line by CSEN monoclonal antibody (M01A), clone 2B3-A1.
Lane 1: KCNIP3 transfected lysate (Predicted MW: 29.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — KCNIP3
Entrez GeneID
30818GeneBank Accession#
BC012850Protein Accession#
AAH12850Gene Name
KCNIP3
Gene Alias
CSEN, DREAM, KCHIP3, MGC18289
Gene Description
Kv channel interacting protein 3, calsenilin
Omim ID
604662Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
A-type potassium channel modulatory protein 3|DRE-antagonist modulator|Kv channel interacting protein 3|calsenilin, presenilin-binding protein, EF hand transcription factor|potassium channel interacting protein 3
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Interactome
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Disease
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