SH3KBP1 monoclonal antibody (M01), clone 1F11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SH3KBP1.
Immunogen
SH3KBP1 (NP_114098.1, 224 a.a. ~ 308 a.a) partial recombinant protein with GST-pstS1 tag.
Sequence
IKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.29 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SH3KBP1 monoclonal antibody (M01), clone 1F11. Western Blot analysis of SH3KBP1 expression in IMR-32.Western Blot (Recombinant protein)
ELISA
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Gene Info — SH3KBP1
Entrez GeneID
30011GeneBank Accession#
NM_031892Protein Accession#
NP_114098.1Gene Name
SH3KBP1
Gene Alias
CIN85, GIG10, MIG18
Gene Description
SH3-domain kinase binding protein 1
Omim ID
300374Gene Ontology
HyperlinkGene Summary
CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001 [PubMed 11474197]).[supplied by OMIM
Other Designations
OTTHUMP00000023022|OTTHUMP00000023024|OTTHUMP00000061480|c-Cbl-interacting protein|migration-inducing gene 18 protein
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Interactome
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Pathway
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