TBX21 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
TBX21 transfected lysate.
Western Blot
Lane 1: TBX21 transfected lysate ( 58.30 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TBX21 full-length
Host
Human
Theoretical MW (kDa)
58.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TBX21 antibody (H00030009-B01) by Western Blots.
SDS-PAGE Gel
TBX21 transfected lysate.
Western Blot
Lane 1: TBX21 transfected lysate ( 58.30 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TBX21
Entrez GeneID
30009GeneBank Accession#
NM_013351.1Protein Accession#
AAH39739.1Gene Name
TBX21
Gene Alias
T-PET, T-bet, TBET, TBLYM
Gene Description
T-box 21
Gene Ontology
HyperlinkGene Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq
Other Designations
T-box expressed in T cells|T-cell-specific T-box transcription factor
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Interactome
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Disease
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