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Last updated: 2016/10/16
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TBX21 monoclonal antibody (M10), clone 2F10

  • Catalog # : H00030009-M10
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant TBX21.
  • Immunogen:
  • TBX21 (NP_037483, 400 a.a. ~ 535 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00030009-M10
    Western Blot detection against Immunogen (40.59 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TBX21 monoclonal antibody (M10), clone 2F10. Western Blot analysis of TBX21 expression in human spleen.
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  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
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  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • TBX21
  • Gene Alias:
  • Gene Description:
  • T-box 21
  • Gene Summary:
  • This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq
  • Other Designations:
  • T-box expressed in T cells,T-cell-specific T-box transcription factor
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