TBX21 monoclonal antibody (M10), clone 2F10
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More Files
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Western Blot (Tissue lysate)
TBX21 monoclonal antibody (M10), clone 2F10. Western Blot analysis of TBX21 expression in human spleen.
Western Blot detection against Immunogen (40.59 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TBX21.
Immunogen
TBX21 (NP_037483, 400 a.a. ~ 535 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RAVSMKPAFLPSAPGPTMSYYRGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.59 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TBX21 monoclonal antibody (M10), clone 2F10. Western Blot analysis of TBX21 expression in human spleen.Western Blot (Recombinant protein)
ELISA
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Gene Info — TBX21
Entrez GeneID
30009GeneBank Accession#
NM_013351Protein Accession#
NP_037483Gene Name
TBX21
Gene Alias
T-PET, T-bet, TBET, TBLYM
Gene Description
T-box 21
Gene Ontology
HyperlinkGene Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq
Other Designations
T-box expressed in T cells|T-cell-specific T-box transcription factor
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Interactome
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Disease
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