EFEMP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EFEMP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EFEMP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EFEMP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EFEMP2
Entrez GeneID
30008GeneBank Accession#
EFEMP2Gene Name
EFEMP2
Gene Alias
FBLN4, MBP1, UPH1
Gene Description
EGF-containing fibulin-like extracellular matrix protein 2
Gene Ontology
HyperlinkGene Summary
A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. [provided by RefSeq
Other Designations
fibulin 4|fibulin-like extracellular matrix protein|mutant p53 binding protein 1
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Interactome
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