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PILRB 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00029990-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PILRB full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 25.08
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PILRB antibody (H00029990-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00029990-T01
    PILRB transfected lysate
    Western Blot
    QC Testing of H00029990-T01
    Lane 1: PILRB transfected lysate ( 25.08 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • PILRB
  • Gene Alias:
  • FDFACT1,FDFACT2
  • Gene Description:
  • paired immunoglobin-like type 2 receptor beta
  • Gene Summary:
  • Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternative splicing has been observed at this locus and three variants, encoding two distinct isoforms, are described. Additional transcript variants have been identified but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • activating receptor PILRbeta,cell surface receptor FDFACT1,cell surface receptor FDFACT2,paired immunoglobin-like receptor beta,paired immunoglobulin-like receptor beta,paired immunoglobulin-like type 2 receptor beta
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