IL19 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IL19 full-length
Host
Human
Theoretical MW (kDa)
24.6
Interspecies Antigen Sequence
Mouse (69)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IL19 antibody (H00029949-D01P) by Western Blots.
SDS-PAGE Gel
IL19 transfected lysate.
Western Blot
Lane 1: IL19 transfected lysate ( 24.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IL19
Entrez GeneID
29949GeneBank Accession#
NM_153758Protein Accession#
NP_715639.1Gene Name
IL19
Gene Alias
IL-10C, MDA1, NG.1, ZMDA1
Gene Description
interleukin 19
Omim ID
605687Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq
Other Designations
melanoma differentiation associated protein-like protein
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Pathway
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Disease
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